Polynucleotides are the most talked-about ingredient in aesthetics right now. Search for them, though, and almost every clinic will tell you the same thing: they're injected. That means needles, small bumps on the skin, possible bruising and a few days of looking "treated".
But what if you could bring polynucleotides into your skincare routine with no injections, no needles and no downtime at all?
At Cosmetier, Dr Rachna Sharma now offers LUMICEN Boost Serum by Toskani Med, a non-invasive polynucleotide serum with a high 3% concentration of PDRN Complex. You simply apply it morning and night, on clean skin, at home. Nothing is injected. Nothing breaks the skin.
In this guide we explain what polynucleotides are, why a needle-free polynucleotide serum is such a big step forward, and whether LUMICEN Boost Serum is right for you.
Polynucleotides are chains of nucleotides, the building blocks of DNA. In aesthetics, they're purified DNA fragments, most often taken from salmon or trout. You may have seen them called PDRN (polydeoxyribonucleotide) or, in the headlines, the "salmon DNA facial".
In clinic, polynucleotides are usually injected. They're popular because they support the skin's own natural renewal, helping to improve hydration, firmness and texture over time.
LUMICEN Boost Serum takes a different, needle-free approach. It's a cosmetic serum applied to the surface of the skin, designed to improve how your skin looks and feels: more hydrated, smoother and visibly firmer.
Unlike dermal fillers, polynucleotides don't add volume or change the shape of your face. Unlike anti-wrinkle injections, they don't affect muscle movement. They're all about skin quality: healthier, stronger, more resilient skin.
Most polynucleotide treatments in the UK are injectable. They're usually given as a course of two to three sessions, using a fine needle or cannula. Clinics often mention numbing cream, small raised bumps ("blebs"), redness, swelling and occasional bruising for a day or two afterwards.
For many people that's simply not an option. You might be nervous of needles, have a busy diary with no room for recovery, or just not feel ready for injectables yet.
LUMICEN Boost Serum changes that. It brings polynucleotides into a light, pearly serum you apply yourself, at home, in seconds.
The serum is dermatologically tested on sensitive skin and suitable for all skin types. There's no recovery period, no "treatment face" and nothing for anyone to notice, except healthier-looking skin.
It also works beautifully alongside clinic treatments. If you do have injectables, peels or a HydraFacial with us, LUMICEN Boost Serum is designed to enhance and prolong those results between appointments.
It isn't a replacement for in-clinic polynucleotide injections, and it doesn't work in the same way. It's a needle-free way to bring polynucleotides into your daily routine.
LUMICEN Boost Serum is made by Toskani Med, a bioregenerative aesthetic medicine brand with polynucleotides at the heart of its range.
3% PDRN Complex. The polynucleotides come from DNA extracted from wild Alaskan salmon. The complex combines two polynucleotide weights, low and medium molecular weight, to help improve skin quality.
Hyaluronic Acid 4D. Four types of hyaluronic acid (cross-linked, high, medium and low molecular weight) work together. They form a protective film and hydrate every layer of the skin, supporting elasticity.
Together, the PDRN Complex and hyaluronic acid help hydrate, smooth and visibly firm the skin.
Key benefits:
In a Toskani clinical study, 30 volunteers aged 25 to 64 used LUMICEN Boost Serum for 15 days. 95% said their skin felt regenerated and repaired.* Measured improvements reached:
The study also recorded visibly less redness and improved skin texture.
That's two weeks of simply applying a serum, with no needles and no downtime. Results vary from person to person (average results may be lower than the maximums shown), and consistent twice-daily use matters.
Toskani clinical study carried out on 30 volunteers between 25 and 64 years old for 15 days.
LUMICEN Boost Serum suits all skin types, including sensitive skin. It's particularly good for you if:
Who should check first? The polynucleotides are derived from salmon DNA, so anyone with a fish allergy should speak to Dr Sharma before using it. It's also not suitable if you avoid animal-derived ingredients.
It takes less than a minute, twice a day:
The texture is pearly and light, so it layers easily under make-up. Each 30ml dropper bottle is designed for daily home use. Dr Sharma will advise exactly where it fits in your routine, especially if you're combining it with other treatments.
Yes. LUMICEN Boost Serum contains polynucleotides (3% PDRN Complex) in a topical serum you apply at home. There are no needles and no injections involved.
No. Injections place polynucleotides directly into the skin in clinic. The serum is a non-invasive cosmetic, applied to the surface of the skin, and works differently. Use it on its own as a needle-free way to improve hydration, texture and firmness, or alongside clinic treatments to help prolong your results.
None. You apply it like any other serum and carry on with your day.
No. There's no needle, no numbing cream and no discomfort. Most people describe the texture as light and silky.
In Toskani's 15-day clinical study, 95% of volunteers said their skin felt regenerated and repaired, with measured gains in hydration, elasticity and firmness. Results vary between individuals.
PDRN stands for polydeoxyribonucleotide, a type of polynucleotide. In LUMICEN Boost Serum it comes from wild Alaskan salmon DNA.
No. Fillers add volume, and Profhilo is a hyaluronic acid bio-remodeller. Polynucleotides focus on supporting the skin's own natural renewal. Many clients combine them.
Yes, we recommend it. Your free video consultation with Dr Sharma confirms whether a polynucleotide serum suits your skin and how it fits with any other treatments.
At Cosmetier, our philosophy is simple: educate first, treat second. Dr Rachna Sharma will only recommend LUMICEN Boost Serum if it will genuinely help your skin.
Dr Sharma is a Save Face accredited dental surgeon (BDS) and aesthetic practitioner, a Member of the Royal College of Surgeons (England) and a Member of the British College of Aesthetic Medicine. Cosmetier is based at The Old Town Hall, Market Square, Toddington, Bedfordshire, close to Luton, Dunstable, Leighton Buzzard and Milton Keynes.
Ready to try polynucleotides without the needles? Book your free, no-obligation video consultation with Dr Sharma, or call us on 01525 611035.